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Protocol Intelligence · v1.0

Apotheon

Research-backed calculators for health optimization.

Peptide reconstitution, GLP-1 escalation charts, evidence-based supplementation, with the source paper linked on the same screen.

Built because I needed citations I could trust for my own protocols. How it works

Start with Peptide Calc
Live data · CI-verified
Source of truth · PubMed ↔ INT-01
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PubMed-verifiedevery citation live-checkedINT-01 guardrailCI-enforced on every buildResearch-firstno MD marketing, no bro-science
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§ I · Injectable protocols

Peptide reconstitution and GLP-1 dosing

View all 4
INJ-01 · Reconstitution math

Peptide Reconstitution Calculator

Exact injection volumes for BPC-157, TB-500, Sermorelin, MOTS-C, and more. Bacteriostatic water to syringe units, solved.

100K+ monthly searches
INJ-02 · GLP-1 escalation

Semaglutide Dosage Chart

Visual escalation for Ozempic / Wegovy with tirzepatide and retatrutide side-by-side. Nausea 30–44% during titration, resolves 4–8 wk.

FDA-approved · weekly SubQ
INJ-03 · Triple agonist

Retatrutide Dosage Chart

Lilly's investigational GIP / GLP-1 / glucagon agonist. 28.7% weight loss at 68 wk; and the 20.9% dysesthesia signal.

Phase 3 · TRIUMPH-4
INJ-04 · Dual GIP/GLP-1

Tirzepatide Dosage Chart

Mounjaro (T2D) + Zepbound (obesity, OSA). Six-step weekly escalation 2.5 → 15 mg. Beats semaglutide head-to-head in SURMOUNT-5 and SURPASS-2. Nausea 30–40% at peak titration, resolves 8–12 wk.

SURMOUNT-1 · 20.9% at 72 wk

§ II · Supplements

Evidence-based, body-weight-scaled, lab-personalized

View all 11
SUP-01 · Body-weight-scaled

Creatine Loading Calculator

0.3 g/kg load, 0.03 g/kg maintenance. Load-then-maintain or direct-maintenance; both end at the same saturation. Serum creatinine rise is the marker, not kidney damage.

500+ RCTs · ISSN-aligned
SUP-02 · Lab-baseline personalization

Vitamin D3 Dose-to-Target

Daily IU from your 25(OH)D baseline, target, and body weight. Cofactor rules for K2 + magnesium.

Heaney serum-dose model
SUP-03 · Goal-based · form picker

Magnesium Dosing Calculator

Elemental mg range + split schedule + recommended form (glycinate, threonate, citrate, taurate, malate) by goal. UL flagged automatically.

600+ enzymatic cofactor reactions
SUP-04 · Ferritin-to-repletion

Iron Deficiency Calculator

Personalized oral iron dose, form, and schedule from your ferritin, sex, and indication. Daily vs alternate-day per the 2026 RCT. Stops on overload, gates on occult-bleed risk.

Severity-aware · GI-workup gate
SUP-05 · Goal-based · copper-offset gated

Zinc Dosing Calculator

Elemental zinc dose, form (bisglycinate / picolinate / acetate lozenge), and copper-offset rule from your goal, sex, diet, and duration. Cold lozenges within the 24 h window only; intranasal zinc contraindicated.

Cold lozenge 24 h window · UL-aware
SUP-06 · Goal-based · metformin-screen aware

Vitamin B12 Dosing Calculator

Goal, diet, metformin exposure, and form preference drive your B12 dose. Refuses to dose replete omnivores per the 2025 Mendelian randomization. Annual-screen flag at 4-year metformin exposure (CUBN rs1801222 modifier).

MR-null in replete adults · ADA 2026 screen
Browse all 11 supplements

§ III · Protocols

Combination protocols with prescription-drug caution

View all 1
HRX-01 · Finasteride + minoxidil

Hair Loss Protocol Calculator

Sex-appropriate finasteride dose + your choice of topical or oral minoxidil. Shedding timeline, LFT schedule, PFS stop rule, LDOM cardiac monitoring surfaced up front.

FDA label · LDOM Delphi · PFS-aware

§ IV · Research Library

Evidence-reviewed, PubMed-verified — 14 peptides + 55 supplements

Browse all 70
MON-01 · Reconstitution evidence base

BPC-157

Pentadecapeptide for soft-tissue repair. FDA Category 1 in 2026 — review the current evidence boundary.

Strong · 27+ PMIDs
MON-02 · Dual GIP / GLP-1

Tirzepatide

Mounjaro / Zepbound clinical monograph. Mechanism, escalation rationale, head-to-head vs semaglutide.

FDA · SURMOUNT / SURPASS
MON-03 · Saturation evidence

Creatine Monohydrate

Why monohydrate beats HCl / ethyl ester / buffered. Non-responder rate, kidney-marker myth.

500+ RCTs · ISSN-aligned
MON-04 · Lab-baseline personalization

Vitamin D3

Cofactor rules for K2 + magnesium. Why most adults under-dose; toxicity threshold + monitoring.

Heaney serum-dose model
MON-05 · Goal-based · 600+ cofactor reactions

Magnesium

Glycinate vs threonate vs citrate vs taurate vs malate. Form picked by goal, not marketing.

Strong · UL-aware
MON-06 · Ferritin-to-repletion

Iron

World's most common nutrient deficiency. Hepcidin window, alternate-day evidence, GI-workup gating.

Strong · 60+ PMIDs

§ V · How Apotheon works

01

Research-cited

Every calculator links to the primary source: PubMed, FDA labels, NEJM, ISSN position stands. The answer and the paper sit on the same screen.

02

No gatekeeping

No login. No email wall in front of the calculator. No free-trial-to-paid funnel. The tool loads; you use it; you leave.

03

Research stays free

Free calculators and research citations, forever. Discreet supplement-brand affiliate links (Thorne, iHerb, Amazon) under supplement calcs fund the work — never AdSense, never ads inside the tools, never product sales on this site.

Apotheon · protocol-intelligence-platform · 2026 · informational only · not medical advice